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71.
Christine Stark Leo M. Condron Alison Stewart Hong J. Di Maureen O’Callaghan 《Biology and Fertility of Soils》2007,43(5):531-540
Because soil biota is influenced by a number of factors, including land use and management techniques, changing management
practices could have significant effects on the soil microbial properties and processes. An experiment was conducted to investigate
differences in soil microbiological properties caused by long- and short-term management practices. Intact monolith lysimeters
(0.2 m2 surface area) were taken from two sites of the same soil type that had been under long-term organic or conventional crop
management and were then subjected to the same 2.5-year crop rotation [winter barley (Hordeum vulgare L.), maize (Zea mais L.), lupin (Lupinus angustifolius L.), and rape (Brassica napus L. ssp. oleifera)] and two fertilizer regimes (following common organic and conventional practices). Soil samples were taken after crop harvest
and analyzed for microbial biomass C and N, microbial activity (fluorescein diacetate hydrolysis, arginine deaminase activity,
and dehydrogenase activity), and total C and N. The incorporation of the green manure stimulated growth and activity of the
microbial communities in soils of both management histories. Soil microbial properties did not show any differences between
organically and conventionally fertilized soils, indicating that crop rotation and plant type had a larger influence on the
microbial biomass and enzyme activities than fertilization. Initial differences in microbial biomass declined, while the effects
of farm management history were still evident in enzyme activities and total C and N. Links between enzyme activities and
microbial biomass C varied depending on treatment, indicating differences in microbial community composition. 相似文献
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Valle L Serena-Acedo T Liyanarachchi S Hampel H Comeras I Li Z Zeng Q Zhang HT Pennison MJ Sadim M Pasche B Tanner SM de la Chapelle A 《Science (New York, N.Y.)》2008,321(5894):1361-1365
Much of the genetic predisposition to colorectal cancer (CRC) in humans is unexplained. Studying a Caucasian-dominated population in the United States, we showed that germline allele-specific expression (ASE) of the gene encoding transforming growth factor-beta (TGF-beta) type I receptor, TGFBR1, is a quantitative trait that occurs in 10 to 20% of CRC patients and 1 to 3% of controls. ASE results in reduced expression of the gene, is dominantly inherited, segregates in families, and occurs in sporadic CRC cases. Although subtle, the reduction in constitutive TGFBR1 expression alters SMAD-mediated TGF-beta signaling. Two major TGFBR1 haplotypes are predominant among ASE cases, which suggests ancestral mutations, but causative germline changes have not been identified. Conservative estimates suggest that ASE confers a substantially increased risk of CRC (odds ratio, 8.7; 95% confidence interval, 2.6 to 29.1), but these estimates require confirmation and will probably show ethnic differences. 相似文献
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